Meet the Newest Cohort of Innovative Health Tech Startups

100ms builds AI agents for patient access, helping patients automate intake, benefits verification, prior authorization, triaging, and scheduling for specialty practices including GI, allergy/immunology, and neurology.

“WFH: Wellness from Home” is a continuous health monitoring platform to enable the elderly to age-in-place healthily, independently and safely. This RPM (remote patient monitoring) platform monitors both vital signs (such as ECG/HR/RR /activity tracking via Nouslogic chest-worn sensor patch with AI model for arrhythmia detection) and real-time medication adherence , together with AI-based medication dispensing capability.

MyBackHub is an AI-powered digital health platform that delivers personalized, non operative back pain care at scale. It combines computer vision, posture and movement analysis, patient reported outcomes, and clinical navigation to triage patients and guide them to the right mix of virtual physical therapy, behavioral health, education, and care coordination. Built with leading academic partners, MyBackHub improves outcomes, increases adherence, and reduces unnecessary imaging, procedures, and surgery. The platform serves consumers, employers, health systems, and payors, and is purpose built for value-based care, including upcoming CMS ACCESS reimbursement for chronic musculoskeletal pain.

Cura.ai builds the context layer for safe, medical-grade AI. Its Patient Context Graph (PCG) unifies fragmented data into a complete, portable, patient-owned medical record that conversational AI uses to deliver instant, evidence-linked explanations. This ensures every interaction is grounded in verified data—improving the accuracy, safety, and portability of healthcare AI while laying the foundation for early risk detection and supervised preventive care.

What if healthcare access adapted to patients, not the other way around? SPRYT’s "Asa" is an AI receptionist that empowers patients to book, change and pay for medical appointments via WhatsApp or text, in their preferred language, anytime. No apps. No website. Think of Asa as a “medical receptionist in your pocket” answering questions, offering reassurance, and coordinating every step of a patient’s care journey. Asa uses AI and behavioral science to anticipate and prevent missed appointments, tailoring communication to each patient. Asa addresses the root causes of no-shows, improving patient access to care while streamlining critical administrative workflows for payers/providers.

The AI of NeoCure aims to prevent 30,000 cases of childhood blindness from ROP, a retinal disease affecting preterm infants. Once blindness occurs, recovery is impossible, and global economic loss exceeds $100B annually. Current detection requires ophthalmologists within 72 hours, yet only 200–300 specialists are available in the U.S. NeoCure’s AI analyzes bedside vital data to enable timely, specialist-free detection. Its proof of concept demonstrates 90% accuracy, and clinical discussions are progressing in Japan and the U.S. NeoCure is committed to protecting vulnerable infants from preventable blindness.

"Xcoo provides “Chrovis,” an AI-powered service supporting cancer genome diagnosis and treatment decisions for medical institutions. Genomic medicine aims to understand diseases at the genomic level and apply this knowledge to patient diagnosis and treatment. Leveraging proprietary cutting-edge information technology, Xcoo provides an interpretation service using in-house developed software ”Chrovis”, which automatically generates reports to support clinicians’ decision making. In addition, it delivers patient-friendly reports that help cancer patients better understand their genomic test results.

YOBO Health addresses the critical gap between hospital discharge and outpatient follow-up that drives preventable readmissions in cardio-renal-metabolic patients. By synthesizing fragmented clinical documentation, social assessments, and care plans into clear, actionable insights, YOBO helps health systems see which patients need immediate intervention and why. The platform supports care teams in delivering targeted, high-touch support at scale, so the right patients receive the right outreach at the right time to prevent costly, avoidable returns to the hospital.

Canary is a patient-centric AI platform for cardio-renal care. The platform identifies high-risk patients early and longitudinally monitors treatment response, safety, adherence, and clinical deterioration using multimodal real-world data. By combining physiology, symptoms, and behavior, Canary enables proactive care interventions and AI-enabled care workflows across the patient journey. The platform generates clinically meaningful real-world insights that support better decision-making for patients and care teams, while also informing healthcare providers, health systems, and life sciences partners on treatment effectiveness and outcomes at scale.

Curenetics is a UK-based health technology and biotechnology company using advanced artificial intelligence to transform cancer care by predicting immunotherapy response. Curenetics' proprietary AI models integrate large-scale clinical, genomic, and imaging data into a single predictive platform, helping clinicians assess how individual patients are likely to respond to immunotherapy treatments before they begin. By layering multiple complex biomarkers rather than relying on single indicators, Curenetics aims to improve treatment precision, reduce unnecessary side effects and costs, and support personalised decision-making in oncology. The company’s tools are designed to be integrated with healthcare systems.

Bluevia Health is an applied AI company improving surgical safety by detecting post-operative deterioration earlier and more reliably. By analyzing multimodal clinical data including EHR records, vitals, labs, and notes. Bluevia builds computed phenotypes and risk intelligence that surface actionable signals clinicians can trust. The platform helps health systems identify complications sooner, reduce failure-to-rescue, and improve outcomes such as length of stay and readmissions. Starting with retrospective quality dashboards and progressing to real-time prediction and intervention, Bluevia enables hospitals to turn existing data into timely decisions, safer surgeries, and more resilient clinical operations.

Precision Imaging Inc. is a Tokyo-based medtech startup specializing in AI-driven intraoperative navigation for orthopedic surgery. Founded by an expert surgeon, the company aims to enhance precision in total hip arthroplasty (THA) by integrating computer vision and medical imaging. Their core product is an AI-based hybrid navigation system that reconstructs 3D pelvic anatomy from 2D fluoroscopic images in real time. By eliminating expensive hardware, they offer a cost-effective alternative to robotic systems. The company’s mission is to democratize high-accuracy surgical guidance globally, improving long-term patient outcomes through data-driven innovation.

Avedian is a healthcare AI company focused on helping hospitals and health systems improve performance, visibility, and operational efficiency. Its platform, Compass Decision Support, combines advanced analytics, machine learning, and generative AI to transform complex hospital data into risk-adjusted, benchmarking, and utilization insights. Compass enables organizations to better understand drivers of length of stay, resource use, care variability, and operational complexity across patient populations. By converting real-world institutional data into actionable operational intelligence, Avedian supports capacity planning, performance optimization, and system sustainability, without providing patient-specific clinical decision support.

Surgery stands as the third leading cause of death worldwide. Hoopcare builds an AI platform to better prepare patients for surgery and anesthesia and reduce postoperative complications. The platform automates preoperative evaluation, optimizes patient readiness, and predicts postoperative events using structured questionnaires and medical records. Hoopcare shifts evaluation upstream, standardizes clinical decisions, and supports clinicians with data-driven insight. The outcomes: safer surgery, lower costs, and improved OR performance.

Hera Fertility is an AI-powered male fertility platform helping individuals, couples, clinics, and donor programs understand and optimize sperm health. By combining convenient testing with predictive AI models trained on 6,000+ patient records, Hera delivers personalized, evidence-based insights that empower patients to take action and help providers improve outcomes. Operating through a nationwide network of 250+ partner labs, Hera serves as intelligent infrastructure for the fertility industry - making male fertility testing accessible, actionable, and normal. Founded by Thiv Paramsothy, a second-time founder who previously exited Adracare to Well Health, Hera is headquartered in New York City.

EW2Health is a digital health company focused on improving obesity and metabolic health through emotionally safe, predictive monitoring technology.** The platform supports GLP-1–based obesity care by continuously tracking weight-related behavior and identifying early signs of disengagement or risk. Using patented Predictive Behavioral Analytics, EW2Health forecasts individual weight trends up to 15 days ahead, enabling proactive, personalized interventions at scale. Integrated into clinical workflows, EW2Health helps providers improve adherence, reduce early dropout, and support sustainable weight loss during and after medication. Validated across multiple international pilots, EW2Health transforms obesity care from reactive check-ins to continuous, data-driven metabolic health management.

EcotoneAI is a frontier AI×biotechnology company redefining how rare diseases are cured. Founded by neuroscientist and second-time founder Dr. eMalick G. Njie, Ecotone builds foundation models from the ground up to analyze 100% of the human genome, unlocking disease-driving genetic mechanisms far beyond the ~1% protein-coding regions traditionally studied. This genetic-mechanism-grounded approach enables precise development of CRISPR, biologic, cell-therapy, and small-molecule medicines. Ecotone’s platform builds on a proven track record in AI-driven genetics, including a $409M pharmaceutical partnership secured by the founder’s prior company, and replaces slow, one-disease-at-a-time wet-lab discovery with scalable frontier AI across thousands of rare diseases worldwide.

OneMedic is a Vietnam-based health-tech company building an AI-driven ecosystem for early detection and chronic disease management. Combining smart technology, modern medical devices, high-quality clinical services, and accessible medical knowledge, OneMedic empowers patients and healthcare providers to manage chronic conditions more effectively. Its integrated platforms connect data from medical devices, personal health records, and AI screening tools to support proactive, continuous care. With a strong focus on real-world impact and patient-centric value creation, OneMedic aims to bring responsible, scalable healthcare innovation to primary care in Vietnam and beyond.