Digital Health Frontier Blog

By John Halamka and Paul Cerrato— Guidelines and guardrails for the safe use of AI require more than regulation. The Coalition for Health AI has created a framework to reduce these risks and improve the safety and effectiveness of these models.

By John Halamka • April 17, 2025

By John Halamka and Paul Cerrato — The capabilities of generative AI continue to grow.  Using them wisely will likely improve clinical decision making.

By John Halamka • April 8, 2025

By John Halamka and Paul Cerrato — The Oxford Dictionary says disease is a disorder of structure or function, especially one that has a known cause and a distinctive group of symptoms, signs, or anatomical changes. It’s time to rethink that simplistic definition.

By John Halamka • April 1, 2025

By John Halamka and Paul Cerrato — In part one, we discussed the shortcomings of evidence-based medicine and the disconnect between RCTs and bedside clinical care. Part 2 explores possible solutions, including machine learning-based algorithms. 

By John Halamka • April 1, 2025

By John Halamka and Paul Cerrato — Evidence-based medicine has benefited patients in countless ways, but there’s a disconnect between EBM and the clinical care that is typically delivered at the bedside. Pragmatic, real-world trials and AI-based algorithms may help solve the problem.

By John Halamka • March 24, 2025

By John Halamka and Paul Cerrato — In part 2 of our series on the basics of digital technology, we explore the deep learning tools that can improve medical image analysis and much more.

By John Halamka • March 18, 2025

By John Halamka and Paul Cerrato — In this new series, we pull back the curtain on the Wizard of Oz to provide plain English explanations about machine learning, artificial neural networks, natural language processing, large language models, and related technology.

By John Halamka • March 12, 2025

By John Halamka and Paul Cerrato — Given their tendency to invent “facts,” several researchers have begun comparing their strengths and weaknesses.

By John Halamka • February 18, 2025

By John Halamka and Paul Cerrato—A well-reasoned, coherent thesis is not enough to convince editorial gatekeepers to accept your article. Consider these additional suggestions.

By John Halamka • January 28, 2025

By John Halamka and Paul Cerrato — Mayo Clinic’s Tapestry Study has demonstrated that next generation genetic analysis can have a significant impact on patient care.

By John Halamka • January 14, 2025